Tiger Woods PGA Tour 10 features the U.S. Open, the USGA Championship and the USGA's Rules of Golf for the first time in the franchise's history.  The Weather Channel (Forecast Channel on the Wii) provides dynamic weather data for the game.  The new "Tournament Challenge" mode allows players to replicate famous shots and moments from the PGA Tour's history. 
There are several new courses available for this version of the game, including Bethpage Black, Pinehurst (Course 2), Torrey Pines, Oakmont, Hazeltine National, Banff Springs, and Turnberry, with all listed courses having hosted major championships before. There are many well-known golfers featured in the game, as well as fictitious golfers.
The Wii version of the game features support for the Wii MotionPlus, allowing for a more authentic sports motion to the golf swing, including the ability to draw and fade. In Europe and North America, the Wii version was available in a bundle with a Wii MotionPlus accessory for limited time at launch. Along with the use of the Wii MotionPlus there is a new Disc Golf option in the game.